Type 2 Diabetes - An Oral Drug That May Protect Against Heart Failure As Well As Lower Blood Sugar

Dapagliflozin (Farxiga) is a SGLT2 inhibitor, given in the form of pills for people who have been diagnosed with type 2 diabetes and used in combination with diet and exercise and sometimes with other medicines. It works by making the kidneys release more sugar into the urine. According to a study reported in October 2018 in the journal Cardiovascular Diabetes, It also helps treat heart failure, a type 2 diabetes complication.

Cardiac failure occurs when the left side of the heart unable to take blood from the lungs and send it out quickly throughout the body.

The heart is made up of muscle tissue that grows when it is stressed. This muscle growth enters a smaller space to accommodate blood flow from the lungs. It causes the heart to fail, filling the lungs with fluid from the blood.

In 2017, approximately 26 million people worldwide suffered from heart failure. Type 2 diabetes in high blood sugar can damage the heart and blood vessels, and high blood pressure can cause. It is important to lower blood pressure to a healthy level to reduce tension in the liver. Heart attacks may not cause chest pain in people with type 2 diabetes because nerve damage reduces sensation. This makes prevention of heart disease even more important.

Investigators at Kobe University and several other research facilities in Japan found 58 people suffering from type 2 diabetes and also heart failure. Dapagliflozin at doses of 5 mg / day was added to their normal regimen. After six months the muscle tissue consisting of the left side of the heart dropped. Brain natriuretic peptide (BNP), a protein secreted by cardiac cells in a prolonged response, lowers BNP levels. From this information, researchers conclude that dapagliflozin may help improve heart failure in people with type 2 diabetes.

Natriuretic peptides are effective in making the kidneys absorb potassium into the kidneys, reducing blood pressure and blood volume in the heart and blood vessels.

Dapagliflozin is given once a day, with or without food. It is set as part of an overall treatment plan that includes nutrition and exercise. Side effects include ...

• urinary tract infections,
• nose stuffed with sore throat,
• regularly drain more urine and at night,
• headache or headache,
• ketoacidosis (check for ketones in urine),
• dizziness and vomiting,
• feeling very tired,
• have difficulty breathing,
• abdominal pain, and
• kidney injury.

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